The Polyendrocrine Metabolic Ovarian Syndrome Association of Australia (POSAA) is urging that the drugs be approved on the PBS for people with the condition, which has no cure and can increase the risk of type 2 diabetes, cardiovascular disease and endometrial cancer.
Symptoms of PMOS include irregular periods, excess hair growth on the body and face, weight gain and hair thinning.
While GLP-1 drugs are not specifically approved by the Therapeutic Goods Administration to treat PMOS, patients are being prescribed them off-label. A University of New South Wales study published in July estimated that half a million Australians use weight-loss medications regularly.
Lorna Berry, a POSAA spokesperson diagnosed with the condition at 32, said she would welcome GLP-1s being subsidised for PMOS patients, alongside funding for evidence-based research.
"It's important for people to have access to medications, irrespective of where they live or where they were born ... it's really important that there's equitable access," she told the Guardian. Berry said some women were missing out because of the high cost, which can run to several hundred dollars each month.
Associate professor Magdalena Simonis, the women's health spokesperson for the Royal Australasian College of Physicians, said the college did not currently have a position on whether GLP-1s were appropriate for managing PMOS.
"They're not necessarily the only tool we have available to us, and that is important because long-term use is expensive, and it doesn't look like these are going to be on the PBS anytime soon, and maybe not ever for conditions such as PMOS," she said. "Because traditionally women's conditions are not included in these changes."
Simonis, a GP with an expert interest in PMOS, said that if research found the medications more effective than existing treatments, a broader discussion about health equity would be needed.
GLP-1 drugs mimic a naturally occurring hormone that helps manage blood sugar levels and reduces hunger. Ozempic is listed on the PBS, but only for the treatment of diabetes. The Pharmaceutical Benefits Advisory Committee has yet to finalise its position on the wider use of the drugs.