Sabatini, known for discovering a protein pathway crucial to understanding cell growth and metabolism in cancer research, ran one of the largest labs at Whitehead Institute, affiliated with MIT. In 2022, colleague Kristin Knouse accused him of sexual harassment after a consensual relationship ended. An internal investigation by Whitehead found that Sabatini had violated institute policies by failing to disclose the relationship and creating a "sexualized undercurrent" in his lab.
He was fired from his post at the institute and from all affiliated biotech startups. Sabatini said he lost everything, lost weight and hair, and cried frequently. Four years later, a jury has awarded him $6 million in a defamation suit against Knouse. The Free Press article, which first profiled Sabatini in 2022, describes the verdict as vindication for the biologist.