Hierarchical implicit models improve compact brain MRI segmentation across sites

By combining features from multiple network layers, HierINRSeg improved both in-domain and cross-site segmentation over a recent implicit neural representation baseline.

Top University
Ziyao Shang · Pouya Sadeghi · Letian Jiang · Alexander Wong · Sirisha Rambhatla

University of Waterloo

Research Digest··2 min read

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INR-based segmentation excels at low parameter budgets and limited augmentation, but U-Nets win with larger capacity.

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The authors compared INR-based and U-Net-based models for brain MRI segmentation across different parameter budgets and training conditions. They found INR models perform best in low-parameter, limited-augmentation settings, while U-Nets benefit more from larger capacity and standard augmentation. They also found segmentation-related information is spread across multiple INR layers, leading them to propose HierINRSeg, which aggregates these layers and outperforms a strong baseline by 5.6 points in-domain and 8.2 out-of-domain.

How it works

before and after
CONVENTIONAL U-NET PIPELINEMRI volumeMRI volumeU-NetU-NetSegmentation mapSegmentation mapHIERINRSEG (PROPOSED)coordinatequerymulti-layerfeaturessegmentati…Coordinate gridCoordinategridINR layersINR layersHierarchical fusionHierarchicalfusionSegmentation mapSegmentationmapFeature fusion across INR layers is the key innovation, improving cross-site robustness.
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