Hugging Face opens DNA model, challenges biology guardrails
Carbon-X and access to biology models
Hugging Face's Thomas Wolf announced Carbon-X, an open 14B DNA model that he says runs on a laptop and approaches frontier-model performance on his team's benchmarks. Leandro von Werra said the team was releasing its training recipe, while Hugging Face CEO Clement Delangue argued that frontier labs' biology guardrails restrict legitimate researchers without stopping bad actors.
On our DNA benchmarks it scores 67%, vs 61% for Claude Opus 5.5 and 50% for Gemini 4 Argon, and its within a point of GPT-6.1 Sol at about 1000x lower cost.
Frontier labs are advancing the capabilities in AI for biology but preventing the good guys (scientists, academia, non-profits, health agencies,...) to use, study and understand it with widespread but shallow guardrails that the bad guys are bypassing easily
clem 🤗, Hugging Face CEO · On XWe are releasing the full recipe, so you can do it, too!
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