
New prostate cell type may explain age-related enlargement
Johns Hopkins researchers identify WIF1+ basal cells as a potential cellular driver of benign prostatic hyperplasia.
Researchers at Johns Hopkins University have identified a distinct subtype of prostate cell that accumulates in the gland's transition zone, offering a new hypothesis for why benign prostatic hyperplasia (BPH) develops with age. The findings, published in The Journal of Pathology, point to WIF1+ basal cells as a potential trigger for the condition that affects millions of men over 50.