Clinical agents learn to gather evidence across longitudinal MRI records

CASE trains a compact vision-language model to select and synthesize relevant clinical evidence rather than answer from preselected inputs.

Chinese Tech
Minye Shao · Chaohui Yu · Yixuan Wu · Fan Wang · Ling Shao · Yang Long

Durham University · DAMO Academy, Alibaba Group · Hupan Laboratory · University of the Chinese Academy of Sciences

Research Digest··2 min read
Shao and colleagues built an interactive benchmark in which agents must investigate patient records and MRI scans from multiple visits before answering clinical questions.

The authors created 50,401 questions from ICD-10-coded diagnoses for 4,739 UK Biobank participants.

Why this paper

From University of the Chinese Academy of Sciences and 3 others

In one line

CASE agents achieve over 16% and 10% relative improvements in answer accuracy over GPT-5.4 and Claude Opus 4.8 on longitudinal medical reasoning.

What we could check

  • ·No code link found
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  • ·No stated limitations found
  • ✓Reports numbers on named benchmarks

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