Archbishop Paul Gallagher, the Vatican's foreign minister since 2014, told the BBC that the news of Pope Leo XIV's ill health was "a bit of a game changer" and "it's going to make things a bit different."
The Pope underwent successful surgery at Rome's Gemelli Hospital on Tuesday to remove the lower lobe of his right lung, after which he was diagnosed with lung adenocarcinoma. The Vatican confirmed the operation proceeded without complications.
Archbishop Gallagher, speaking on Tuesday after the operation was announced but before the cancer diagnosis was made public, said: "I think we were maybe taking him a little bit for granted." He contrasted Pope Leo with his predecessor, noting that after the latter years of Pope Francis, who used a wheelchair, "Pope Leo comes along and he's sporty and he seems to be in excellent health, and now we're told that he's not in excellent health and things have got to be sorted out."
The Archbishop expressed concern but also hope, drawing on personal experience: "Lots of us have been through similar experiences at different times in our lives, and we've got through them, and so we hope it's going to be the same case with Pope Leo." He added that the diagnosis might change assumptions within the Church, which had viewed the Pope as less vulnerable than others.