Pretrained transformer estimates longitudinal causal effects for dynamic treatment policies

PICLE-PFN predicts conditional average potential outcomes across datasets and horizons in one forward pass, without retraining or hyperparameter tuning.

Big Tech
Wenxin Chen · Kyra Gan · Mingyu Lu · Zilin Jing · Fei Wang · Hoifung Poon · +2 more

Cornell University · University of Washington · Columbia University · Recursion Pharmaceuticals, Inc. · Microsoft Research

Research Digest··2 min read
Illustration: Pretrained transformer estimates longitudinal causal effects for dynamic treatment policies
The authors introduce PICLE-PFN, the first foundation model for longitudinal causal effect estimation that supports both static and dynamic treatment policies.

Longitudinal causal effect estimation from observational data is complicated by time-varying confounding and treatment-confounder feedback loops.

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